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This matchup between No. 12 Southern Miss and No. 5 Oregon will definitely feature a lot of points. There could be around 90 points for this game, both Oregon and Southern Miss have prolific offenses, Oregon more than Southern Miss, and each have average defenses. Oregon's defense is more opportunistic with a plus-nine turnover margin and average over three sacks per game while Southern Miss is at minus-two in turnover margin.
| Oregon |
Southern Miss |
| 46.2 PPG | 37.8 PPG |
| 515.2 Total YPG | 471 Total YPG |
| 295.69 Rushing YPG | 207.77 Rushing YPG |
| 219.50 Passing YPG | 263.2 Passing YPG |
| 23.6 Points allowed per game | 21.1 Points allowed per game |
| 381.0 Yards allowed per game | 345.3 Yards allowed per game |
| 137.46 Rushing yards allowed per game | 112.62 Rushing yards allowed per game |
| 243.5 Passing yards allowed per game | 232.7 Passing yards allowed per game |
| +9 Turnover margin | -2 turnover margin |
| 3.31 Sacks per game | 1.92 Sacks per game |
There is no question to me that Oregon would win, but Southern Miss will be able to put some points. The difference will be that Oregon's defense creates turnovers and will be able to stop Southern Miss' offense more often than Southern Miss will be stopping the Oregon offense.
My final score prediction will be Oregon 56 Southern Miss 27
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